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The most common consequence is lipohypertrophy (firm, lumpy thickening of the fat layer), which is well documented in people who inject insulin at the same site

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The anti-CD20 therapies lead to elimination of CD20 expressing pre-B cells and mature lymphocytes via a variety of mechanisms, including antibody-dependent cellular cytotoxicity (ADCC), antibody-dependent cellular phagocytosis, complement-dependent cytotoxicity (CDC), cell death via apoptosis and decreased antibody production (155) (Figure 3)